I'm in the process of completely rewiring my S2 so of course that includes fuse upgrades. I have essentially all the wiring ripped out (for a few years, if we're being honest, but hopefully not for much longer!) and have been furiously planning out my updated wiring. The plan is to use a pair of Blue Sea fuseboxes:
https://www.amazon.com/gp/product/B000K2MBPAI had heard them recommended at some point. The downside is that there's just a single power coming into them, so one will be for things that only run when the car is on, the other for things that run all the time (headlights, etc.)
I don't have my wiring plans in front of me, but I have one 6-fuse w/cover in hand and will be ordering a matching one, for a total of 12 fuses; I think I have plans for 11 of them.
I have been chatting with someone in Australia (ordering a CV joint conversion) and they recommended RCDs mounted in the cabin; I hadn't heard that term here in the USA but apparently it's what we'd call a ground fault interrupt breaker here, so you just reset it rather than replacing a fuse. I didn't go that way but I'm still trying to work out just where the fuses will go; I'm not concerned about looking original but I don't want them to be impossible to access, either.
The hardest part I've had is figure out just what size wiring to order; I'm using all original Lucas colors but certain things need heavier wire and I'm trying to do the math to figure out where I need it based on amperage; it's a pain but theoretically only needs to be done once!